Speakers

Keynote Speakers

Douglas GreenDouglas Green
St. Jude Children's Research Hospital, Memphis 

Speaker Profile

Doug Green PhD holds the Peter C. Doherty Endowed Chair of Immunology at St. Jude Children's Research Hospital. Doug received his PhD from Yale. He joined the faculty at the University of Alberta in Edmonton in 1985, and in 1990 became Member and Head of the Division of Cellular Immunology at the La Jolla Institute for Allergy and Immunology in San Diego, where he worked until 2005, when he became chair of Immunology of St. Jude Children's Research Hospital. His research has focused on the process of active cell death and cell survival, extending from the role of cell death in cancer regulation and immune responses in the whole organism to the fundamental molecular events directing the death of the cell. Doug has published over 500 research papers, reviews, and book chapters, and is an ISI “highly cited” investigator in the fields of Immunology and Molecular Biology.  He has also written over 100 columns about aspects of biomedical research for the Journal of Cell Science, under the pseudonym, “The Mole.”

 

Ruslan MedzhitovRuslan Medzhitov
Howard Hughes Medical Institute / School of Medicine, Yale University, Connecticut

Speaker Profile

Ruslan Medzhitov obtained his undergraduate degree from Tashkent State University in 1990 and his doctoral degree from Moscow State University in 1993. In 1999 he joined the faculty at Yale University School of Medicine where he is currently the David W Wallace Professor of Immunobiology and an investigator of the Howard Hughes Medical Institute. His research interests include biology of inflammation, innate immunity, allergy, cell signaling and gene regulation.  He is a member of the National Academy of Sciences, National Academy of Medicine, and European Molecular Biology Organization, and he is a fellow of the American Academy of Microbiology.


Invited Speakers

Immuno-Metabolism and Innate Immunity

Maxim ArtyomovMaxim Artyomov
Washington University, St. Louis, USA 

Speaker Profile

Maxim Artyomov is an Assistant Professor in the Pathology and Immunology Department at Washington University in St Louis leading its Systems Immunology Laboratory. Maxim completed his PhD at MIT in the field of computational immunology working in Arup Chakraborty’s Lab, and then worked as a postdoctoral researcher at the Broad Insitute in Aviv Regev’s group working on high-throughput RNA-seq approaches and analysis of the transcriptional regulation in dendritic cells. Maxim's Lab is focused on dissecting immune phenotypes and regulation using high-throughput techniques for data generation, analysis and integration, with a special focus on transcriptional, metabolomic and epigenetic data.

 

Steve BesingerSteve Besinger
David Geffen School of Medicine, UCLA, Los Angeles, USA

Speaker Profile

Dr Bensinger is an associate professor in the Department of Microbiology, Immunology and Molecular Genetics at the David Geffen School of Medicine, University of California, Los Angeles (UCLA). He received his Veterinary Medical Degree (VMD) in 1998 and PhD in Immunology (2003) in the laboratory of Dr Laurence Turka from the University of Pennsylvania. Dr Bensinger completed a postdoctoral fellowship in the laboratory of Dr Peter Tontonoz (HHMI, UCLA). In 2008 he joined the faculty of the Institute for Molecular Medicine at UCLA. Dr Bensinger also serves as Director of Shared Resources at the Jonsson Comprehensive Cancer Center (UCLA). 

 

Navdeep ChandelNavdeep Chandel
Feinberg School of Medicine, Northwestern University, Chicago USA

Speaker Profile

Navdeep S Chandel, is the David W. Cugell Professor of Medicine and Cell Biology at the Feinberg School of Medicine, Northwestern University. He graduated from the University of Chicago with a BA in mathematics and PhD in cell physiology. Dr Chandel’s work revolves on understanding how mitochondria act as signaling organelles to regulate physiology and pathology. Historically, mitochondria have been primarily viewed as biosynthetic and bioenergetic organelles. His work has elucidated that mitochondria participate in signaling by releasing reactive oxygen species and metabolites, which regulate distinct biological outcomes including differentiation, proliferation, and metabolic stress in the context of cancer, immunity and stem cells. 

 

Heather ChristofkHeather Christofk
David Geffen School of Medicine,  UCLA, Los Angeles, USA

Speaker Profile

Heather Christofk is an Associate Professor in the Departments of Molecular and Medical Pharmacology and Biological Chemistry at UCLA.  Her research focuses on the regulation and role of metabolic transitions in cellular transformation, virus infection, and differentiation. By elucidating regulatory mechanisms for metabolic transitions in normal and disease states, she hopes to identify diagnostic and treatment strategies for cancer patients.  She received a bachelor’s degree from UCLA, a doctorate from Harvard University under the mentorship of Dr Lewis Cantley, and conducted postdoctoral research with Dr Frank McCormick at UCSF.  Dr Christofk is a Searle Scholar and has been awarded a Damon Runyon-Rachleff Innovation Award, an NIH Director’s New Innovator Award, and an American Cancer Society Research Scholar Award.

 

Vishwa Deep DixitVishwa Deep Dixit
Yale School of Medicine, New Haven, Connecticut, USA

Speaker Profile

Vishwa Deep Dixit completed Bachelor and Master of Veterinary Sciences in HAU, Hisar India. Thereafter, he received German Academic Exchange Service fellowship to conduct PhD research in Germany. He completed PhD coursework in HAU and Research Work in University of Hannover in Year 2000. He conducted postdoctoral research training in NIH then joined Pennington Biomedical Research Center as an Assistant Professor in 2006 and moved to Yale as Professor of Comparative Medicine and Immunobiology in 2013. Dixit’s research is focused on understanding the interactions between metabolic and immune systems with the goal to reveal molecular targets that can be harnessed to control inflammation and immune dysfunction as means to enhance the healthspan. The research in the Dixit Laboratory is funded by the National Institutes of Health (NIA, NIAID and NIDDK.)

 

Vishva M DixitVishwa M Dixit
Genentech, Inc, New York, USA

Speaker Profile

Vishva M Dixit is Vice President of Physiological Chemistry at Genentech, Inc. His interests include cell death, NF-kB signaling, the role of ubiquitin modification in disease pathogenesis, and characterizing regulatory complexes within the innate immune system, especially, the Inflammasome. A historical perspective of his contributions is documented in three accounts published in Nature (2008, 453:271-273), Nature Cell Biology (2010, 12(5): 415) and The Journal of Immunology (2013, 190:3-4).  He is a Foreign Member, European Molecular Biology Organization, a member of the National Academy of Medicine, the American Academy of Arts and Sciences and the National Academy of Sciences. 

 

Eicke LatzEicke Latz
Institute of Innate Immunity, University of Bonn, Germany

Speaker Profile

Eicke Latz is directing the Institute of Innate Immunity at the University of Bonn, which focuses on identifying the most proximal mechanisms of innate immune activation in chronic inflammatory diseases. He is also Adjunct Full Professor at UMass Medical School at the Division of Infectious Diseases and Immunology, Adjunct Professor at the Centre for Molecular Inflammation Research at the Norwegian Technical University in Trondheim and he heads a research group at the German Center for Neurodegenerative Diseases (DZNE) in Bonn. He is listed in the World’s Most Influential Minds by Thompson Reuters and is listed as a highly-cited scientist in immunology in 2014 and 2015.

 

Lydia LynchLydia Lynch
Harvard Medical School, Boston, USA

Speaker Profile

Lydia Lynch’s Lab studies the cross-talk between the innate immune system and the metabolic system, and the key molecules involved. A major focus is to understand the effects of metabolic disorder, such as obesity or the tumor microenvironment, on the innate immune system. We focus on NK cells, and ‘unconventional’ non-MHC restricted T cells including iNKT cells and T cells. Lydia received a PhD in Immunology in Ireland and trained in the labs of Prof Michael Brenner and Prof Uli von Andrian in Harvard. Lydia is the recipient of a UNESCO-L’Oreal International Woman in Science Award, a Marie Curing Fellowship and an American Diabetes Association Faculty Award.

 

Seth MastersSeth Masters
Walter and Eliza Hall Institute of Medical Research, Melbourne.Australia

Speaker Profile

The Masters laboratory studies the innate immune system, which can be activated to cause autoinflammatory disease. A particular focus in this area has been the inflammasome protein complex which generates the cytokine IL-1b. Specifically, Dr Masters and colleagues discovered mutations that activate the Pyrin inflammasome in a dominantly inherited disease they called PAAND, which lead to successful therapy by blocking IL-1b. The NLRP1 inflammasome has also been an active area of research, with links to obesity and metabolic syndrome. Previous work of note includes activation of the NLRP3 inflammasome by IAPP amyloid, and discovery of the autoinflammatory disease DIRA, due to mutations in IL-1Ra.

 

Luke O’NeillLuke O’Neill
Trinity Biomedical Sciences Institute: Trinity College, Dublin, Ireland

Speaker Profile

Luke O’Neill is the Professor of Biochemistry in the School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute Trinity College Dublin. His research area is the molecular basis to innate immunity and inflammation, with a particular interest in TLRs, inflammasomes and metabolic reprogramming.  He was elected a Fellow of the Royal Society in 2016 for his work on innate immunity and inflammation.

 

Erika PearceErika Pearce
Max Planck Institute for Immunobiology and Epigenetics, Freiburg, Germany

Speaker Profile

Dr Pearce obtained her PhD in 2005 at the University of Pennsylvania in Philadelphia on the regulation of T cell responses during infection. During her postdoctoral studies at the University of Pennsylvania she began her research into how cellular metabolic processes govern immune responses to infection and cancer. In 2009, Dr Pearce began her independent research career as an Assistant Member at the Trudeau Institute in Saranac Lake, NY.  In 2011 she moved to Washington University in St. Louis as an Assistant Professor. In 2015, Dr Pearce became a Director at the Max Planck Institute for Immunobiology and Epigenetics in Freiburg, Germany. Her research continues to investigate metabolic pathways in immune cells, with a view to targeting these pathways for therapy.

 

Kate SchroderKate Schroder
Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia

Speaker Profile

Kate Schroder heads the Inflammasome Laboratory at the Institute for Molecular Bioscience, University of Queensland, as an ARC Future Fellow. Kate’s PhD studies defined novel macrophage activation mechanisms (awarded 2005). Her subsequent postdoctoral research identified surprising inter-species divergence in the inflammatory programs of human versus mouse macrophages. As an NHMRC CJ Martin Fellow in Switzerland, Kate trained with the pioneer of inflammasome biology, Jürg Tschopp, and gained expertise in this area. Her current research interests include the molecular mechanisms governing inflammasome activity and caspase activation, the cellular mediators of inflammasome-dependent inflammation, and inflammasome suppression by autophagy and small molecule inhibitors. 

 

Microbiome and Adaptive Immunity

Janelle AyresJanelle Ayres
Salk Institute for biological studies, La Jolla, USA

Speaker Profile

Janelle Ayres completed her PhD a Stanford University and her postdoctoral studies at UC Berkeley before joining the Salk Institute on Faculty. In a new approach to therapeutics, Janelle studies how the body controls and repairs the collateral damage generated during interactions with bad microbes. She is taking an innovative approach grounded in mathematical and evolutionary predictions that uses the beneficial microbes that inhabit our digestive system for damage-control therapeutics. In pivotal work, she showed that those damage-control mechanisms are just as important as an animal’s immune system in surviving infection. Janelle's ultimate goal is to develop treatments for infectious and non-infectious diseases (such as pathologies associated with cancer and aging) without the need for antibiotics.

 

Susan KaechSusan Kaech
Yale University, New York, USA

Speaker Profile

Susan Kaech received her PhD In Developmental Biology at Stanford University in 1999 with Dr Stuart Kim studying the regulation of cell fate decisions and tissue patterning in the worm vulva. She then moved across the country to Hot-lanta to work with Dr Rafi Ahmed to study how cell fate decisions are made in the immune system and focused on the development of T cell memory.  With Dr Rafi Ahmed she mapped out some of the first details of how and when memory T cells form following acute viral infection. She then started her own lab at Yale University in the Department of Immunobiology in 2004 and proceeded to decode the genetic pathways controlling the formation of memory T cells and their progenitors. More recently, she has focused on how particular nutrients and metabolic pathways influence the function and survival of memory T cells following viral infection and in tumors.

 

Dan LittmanDan Littman
Howard Hughes Medical Institute / Skirball Institute of Biomolecular Medicine of New York University, New York, USA

Speaker Profile

Dr Littman’s laboratory studies how T lymphocytes develop and participate in inflammation and how HIV interacts with the host innate immune system. His laboratory currently focuses on elucidating the mechanisms through which microbiota guide the differentiation of distinct types of T lymphocytes and thus influence autoimmune disease.   Dr Littman completed an MD/PhD at Washington University and was a postdoctoral fellow in Richard Axel’s laboratory at Columbia University. He was on the faculty at the University of California, San Francisco, before joining NYU, where he is Professor of Molecular Immunology at the Skirball Institute of Biomolecular Medicine and an Investigator of the Howard Hughes Medical Institute.

 

Cancer Metabolism

Brendan ManningBrendan Manning
Harvard University’s T.H. Chan School of Public Health, Boston, USA

Speaker Profile

Brendan Manning is a Professor in the Department of Genetics and Complex Diseases and Director of the PhD Program in Biological Sciences at Harvard University’s TH Chan School of Public Health. He received his PhD from Yale in 2000 and then joined the laboratory of Lewis Cantley at Harvard Medical School for his postdoctoral research. He discovered that the TSC tumor suppressors serve as the molecular link between the PI3K and mTOR pathways. Research in his lab remains focused on the PI3K-mTOR signaling network and its control of metabolism. In 2015, Dr Manning became an inaugural recipient of the National Cancer Institute’s Outstanding Investigator Award. 

 

Christian MetalloChristian Metallo
University of California, San Diego, USA

Speaker Profile

Christian Metallo studies metabolism in cells, tissues, and animals. His laboratory integrates analytical chemistry, cell biology, and engineering approaches to understand how metabolic dysfunction contributes to cancer and diabetes. Christian is currently an Assistant Professor in Bioengineering at the University of California, San Diego. He received his BS from the University of Pennsylvania before joining Merck in 2000.  He received his PhD in Chemical Engineering from the University of Wisconsin-Madison and was an ACS postdoctoral fellow at MIT.  Christian was the recipient of the 2012 BMES Young Investigator Award, a 2013 Searle Scholar Award, and a 2015 NSF CAREER Award.

 

Ralph DeBerardinisRalph DeBerardinis
The Children’s Medical Center Research Institute (CRI), University of Texas Southwestern Medical Center, Dallas, USA

Speaker Profile

Ralph J DeBerardinis is interested in how altered metabolism contributes to disease. He obtained his MD and PhD from the University of Pennsylvania, and clinical expertise in Pediatrics and Medical Genetics at The Children’s Hospital of Philadelphia. Dr DeBerardinis is Associate Professor in the Children’s Medical Center Research Institute (CRI) at the University of Texas Southwestern Medical Center. He holds the Joel B. Steinberg, MD Chair in Pediatrics and is clinical Division Chief of Pediatric Genetics and Metabolism. The DeBerardinis laboratory focuses on identifying metabolic pathways required for tumor cell growth, and on developing methods to analyze metabolism in vivo. In 2013, Dr DeBerardinis established the Genetic and Metabolic Disease Program in the CRI, which seeks to synergize clinical and research efforts at UT Southwestern to discover, understand, and treat metabolic diseases in children.

 

Russell JonesRussell Jones
Goodman Cancer Research Centre at McGill University, Montreal, Canada

Speaker Profile

Dr Russell (Rusty) Jones is an Associate Professor in the Department of Physiology and Goodman Cancer Research Centre at McGill University. Dr Jones received his PhD in Medical Biophysics in 2003 from the University of Toronto, and completed postdoctoral training with Dr Craig Thompson at the University of Pennsylvania. His research focuses on investigating the genetic and biochemical pathways that control metabolic reprogramming in cancer and the immune system. Dr Jones investigates how our understanding of cellular metabolism can be used to target metabolic vulnerabilities of cancer cells and to enhance immune responses to cancer through metabolic interventions. Dr Jones is a William Dawson Scholar of McGill University and the recipient of the Dorval Young Investigator Prize from the Canadian Cancer Society. His work is supported by Canadian Institutes of Health research (CIHR), The Canadian Cancer Society, The Terry Fox Foundation, and The Canadian Foundation for Innovation.

 

Michael KarinMichael Karin
University of California, San Diego, USA

Speaker Profile

Michael Karin has spent his entire academic career investigating stress and inflammation signaling covering the entire gamut of research approaches from basic biochemistry through molecular cell biology to animal pathophysiology. After discovering how environmental stress caused by either infection, inflammation or exposure to toxic substances leads to activation of AP-1, NF-κB and other transcription factors, his lab began to examine the role of the key signaling pathways controlling these transcription factors in the pathogenesis of cancer, degenerative and metabolic diseases. Through this work, Dr Karin has contributed to the founding of the Inflammation and Cancer field.

 

Reuben ShawReuben Shaw 
Salk Institute for Biological Studies, La Jolla, USA

Speaker Profile

Professor Shaw research in the Shaw lab at the Salk Institute focuses on the AMPK pathway, a central energy-sensing pathway in all eukaryotic cells that reprograms metabolism in low nutrient conditions.  After receiving his PhD at MIT and postdoctoral training at Harvard Medical School, Shaw started at the Salk Institute as an Assistant Professor in 2006.  He was the recipient of several young investigator awards including the Howard Hughes Medical Institute Early Career Scientist Award.  In 2014 he was promoted to Full Professor and in January 2016, he succeeded Tony Hunter to become the Director of the Salk NCI-Designated Basic Cancer Center.  

 

Erwin WagnerErwin Wagner
CNIO, Madrid, Spain

Speaker Profile

Professor Wagner obtained his PhD in 1978 for studies on bacterial genetics in Berlin. He did his postdoctoral training with Beatrice Mintz in Philadelphia (1979-83), became a Group Leader at EMBL, Heidelberg (1983-88) and from 1988 he was Senior Scientist and Deputy Director at the IMP Vienna, Austria. Since 2008 he became Vice Director (2008-11) and Director of the Cancer Cell Biology Program at the CNIO, Madrid. His work focuses on understanding gene functions in mammalian development and disease/cancer, employing genetic mouse models for human diseases with a focus on understanding the functions of the AP-1(Fos/Jun) transcription factor complex. 

 

Obesity, Inflammation and Metabolism

Marc DonathCarolin Daniel
Helmholtz Diabetes Centre, Munich, Germany

Speaker Profile

Carolin obtained a Ph.D. in Immune pharmacology from the European Graduate School of the German Research Foundation in Frankfurt (Germany) and the Karolinska Institute in Stockholm (Sweden) in 2008. With a Fellowship from the Leopoldina/National Academy of Sciences Germany she did a Post-Doc in Immunology at the Dana Farber Cancer Institute in the laboratory of Harald von Boehmer and a joint appointment with Harvard Medical School, Boston (MA/USA). From 2012-2016 she was heading a Young Investigator Group on Immune Tolerance in Type 1 Diabetes and since 2017 she is an independent Research Group leader focusing on T cell tolerance in diabetes and obesity at the Helmholtz Diabetes Center of the Helmholtz Zentrum München, Germany. Her research interests focus on T cell tolerance induction in diabetes, mechanisms of tissue-specific tolerance as well as humanized mouse models.

 

Marc DonathMarc Donath
University of Basel, Switzerland

Speaker Profile

Marc Y Donath is Head of the Clinic for Endocrinology, Diabetes and Metabolism at the University Hospital of Basel, Switzerland, and Professor for Endocrinology at the University of Basel. His main scientific contribution is the description of an inflammatory process underlying beta cell failure and apoptosis in type 2 diabetes, with a central role for IL-1beta. On the basis of this he initiated a pioneering clinical trial in patients with type 2 diabetes that vindicates his hypothesis and opens the way for a causative treatment and prevention of diabetes. These studies have now entered the phase 3 of clinical trials. Beyond his special focus on the beta cell he has shown that elevated IL-6 mediates a cross talk between insulin sensitive tissues, L cells and pancreatic islets to adapt to changes in insulin. Finally, recently Dr Donath has uncovered the first monogenic form of type 1 diabetes. Overall this research has contributed to the concept that the innate immune system is part of the regulation of metabolism

 

Mark FebbraioMark Febbraio
Garvan Institute of Medical Research, Sydney, Australia

Speaker Profile

Professor Mark Febbraio is a Senior Principal Research Fellow of the NHMRC, is the Head of the Cellular and Molecular Metabolism Laboratory and Head of the Division of Diabetes and Metabolism at the Garvan Institute of Medical Research in Sydney, Australia. He is also the Chief Scientific Officer of N-Gene Research Laboratories Inc, a USA-based Biotechnology Company. His research is focused on understanding cellular and molecular mechanisms associated obesity, inflammation and type 2 diabetes and his aim is to develop novel drugs to treat metabolic and inflammatory diseases. Professor Febbraio is also dedicated to health and fitness and continues to compete in running races and multi-sport events. 

 

Edward PearceEdward Pearce
Max Planck Institute for Immunobiology and Epigenetics, Freiburg, Germany

Speaker Profile

Professor Edward Pearce studied for his PhD at the NIMR in London.  His postdoctoral training was in Alan Sher’s laboratory at the NIH in Bethesda. He took his first faculty position at Cornell University (Ithaca), and has since held positions at the University of Pennsylvania, the Trudeau Institute, and Washington University School of Medicine. In 2015 he moved to Freiburg, where he is a Senior Group Leader at the Max Planck Institute of Immunobiology and Epigenetics, and a Professor of Biology at the University.  His work explores type 2 immunity and, increasingly of late, the role of metabolic reprogramming in innate immune cell function.

  

Alyssa HastyAlyssa Hasty
School of Medicine, Vanderbilt University, Nashville, USA

Speaker Profile

Dr Alyssa Hasty earned her PhD at Vanderbilt University in the laboratory of Dr Sergio Fazio and then completed a postdoctoral fellowship at Tokyo University in the laboratory of Dr Hitoshi Shimano.  She was recruited back to Vanderbilt in 2003 as an Assistant Professor in the Department of Molecular Physiology and Biophysics.  Dr Hasty is interested in graduate education and career development of junior faculty members.  She is a leader in the study of the role of macrophages in obesity and metabolic disease with a special emphasis on macrophage iron handling.  

 

Andrea HevenerAndrea Hevener
David Geffen School of Medicine, UCLA, Los Angeles, USA

Speaker Profile

Andrea Hevener is a Professor in the Division of Endocrinology, Diabetes, and Hypertension at the UCLA David Geffen School of Medicine. Dr Hevener’s laboratory studies the transcriptional regulation of immunometabolism with a specific focus on the role of nuclear receptors in controlling mitochondrial energetics and immune cell function. Recently, Dr Hevener’s team showed that the estrogen receptor (ER) α is critical for regulating mitochondrial dynamics and metabolism in macrophages. Importantly, impaired myeloid-specific ERα action contributed to macrophage dysfunction and promoted an obesity-insulin resistance-atherosclerosis susceptibility phenotype in female mice. Dr Hevener is an executive committee member of the UCLA Iris Cantor Women’s Health Research Center and the NIH-sponsored UCSD-UCLA Diabetes Research Center

 

Takashi KadowakiTakashi Kadowaki
School of Medicine, University of Tokyo, Japan

Speaker Profile

Takashi Kadowaki is currently Professor and Chairman of the Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, at the University of Tokyo.  He served as Director of the University of Tokyo Hospital and is the Chairman of the Board of Directors of The Japan Diabetes Society. His major research interests include molecular basis of insulin resistance and type 2 diabetes, and molecular mechanisms of adiponectin action and adiponectin receptors. He served as an editorial board member of Diabetes and Journal of Clinical Investigation and currently is on the editorial board of Cell Metabolism.

 

Diane MatthisDiane Mathis
Harvard Medical School, Boston, USA

Speaker Profile

Dr Mathis obtained a PhD from the University of Rochester, and performed postdoctoral studies at the Laboratoire de Génétique Moléculaire des Eucaryotes in Strasbourg and at Stanford University Medical Center. She returned to Strasbourg at the end of 1983, establishing a laboratory at the LGME (later the Institut de Genetique et de Biologie Moleculare et Cellulaire), in conjunction with Dr Christophe Benoist. The lab moved to the Joslin Diabetes Center, Boston in 1999. Through 2008, Dr Mathis was a Professor of Medicine at Brigham and Women’s Hospital and Harvard Medical School, and Associate Research Director and Head of the Section on Immunology and Immunogenetics at Joslin. Dr Mathis is currently a Professor in the Department of Microbiology and Immunobiology at HMS, and holder of a Morton Grove-Rasmussen Chair in Immunohaematology. She is also a Principal Faculty Member at the Harvard Stem Cell Institute and an Associate Faculty Member of the Broad Institute. She presently serves on Scientific Advisory Boards of the HHMI, Genentech, MedImmune, and Pfizer, and of several research institutes worldwide.  Dr Mathis was elected to the US National Academy of Sciences in 2003, the German Academy in 2007, and the American Academy of Arts and Sciences in 2012.

 

Philipp SchererAndrew Pospisilik
Max Planck Institute for Immunobiology and Epigenetics, Freiburg, Germany

Speaker Profile

Born in Vancouver, Andrew did his PhD in Physiology, demonstrating therapeutic potential of DPIV-inhibition. He joined Josef Penninger to witness the birth of IMBA, a new flagship institute for Austrian science, where he broke a dogmatic link between mitochondrial dysfunction and diabetes and identified one of the first known controllers of good (brown) versus bad (white) fat development and function. Andrew’s current focus is to understand the mechanisms underpinning phenotypic variation and how these steer evolution, adaptation and disease. This work has included identification of genetic switches capable of establishing bi-stability in mammalian development (polyphenism) as well as intergenerational reprogramming. He is a member of multiple international consortia aiming to bridge epigenetic and complex disease research including the International Human Epigenome Consortium (IHEC/DEEP). His work has been recognized by two ERC grants, the GSK award for Basic Medical Research, the EASD Rising Star Award and the HelDI young investigator award.

 

Philipp SchererPhilipp Scherer
Touchstone Diabetes Center, University of Texas Southwestern Medical Center, Dallas, USA

Speaker Profile

Philipp Scherer is Professor and Director of the Touchstone Diabetes Center at the University of Texas Southwestern Medical Center in Dallas. Throughout his career, he has maintained an interest in processes related to cellular and systemic energy homeostasis. Current efforts in his laboratory are focused on the identification and physiological characterization of novel proteins that serve as potential links between the adipocyte, liver, the pancreatic beta cell and the processes of whole body energy homeostasis, inflammation, cancer and cardiovascular disease. 

 

Steve ShoelsonSteve Shoelson
Harvard Medical School, Boston, USA

Speaker Profile

Dr Shoelson, an internationally recognized leader in diabetes research, is a Professor of Medicine at Harvard Medical School and the Helen and Morton Adler Chair, Head of the Section on Pathology and Molecular Pharmacology, and Associate Director of Research at the Joslin Diabetes Center.  His PhD (chemistry) and MD degrees were from the University of Chicago. His numerous awards and honors include a Burroughs Wellcome Fund Scholar Award in Experimental Therapeutics, the Excellence in Diabetes Research Award of the Juvenile Diabetes Research Foundation, the Caledonian Prize of the Royal Society of Edinburgh, and the Donald F Steiner Award for Outstanding Achievement in Diabetes Research. He is known for studies attempting to pioneer new approaches for treating and preventing type 2 diabetes and cardiovascular disease.

 

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