*Program content may be subject to change.

Sunday August 13th     
14.00-17.00 Registration  Talanoa Hall
Welcome & Opening Address    Talanoa Hall

Mark Febbraio
Garvan Institute of Medical Research, Sydney, Australia
Erika Pearce
Max Planck Institute for Immunobiology and Epigenetics, Freiburg, Germany
Mitochondrial Shape Shifting in the T Cell Response
Session 1: Immuno-Metabolism I
Session Chair: Luke O'Neill
    Talanoa Hall
18.00-18.30 Michael Karin
University of California, San Diego, USA

18.30-19.00 Steve Bensinger
David Geffen School of Medicine, UCLA, Los Angeles, USA
Towards Understanding the Impact of Lipid Metabolic Programming in Inflammatory and Immune Responses
19.00-19.30 Navdeep Chandel
Feinberg School of Medicine, Northwestern University, Chicago, USA
Mitochondria as Signaling Organelles
19.30-19.45 Short talk
Ana Domingos
Gulbenkian Science Institute, Oeiras, Portugal
Sympathetic Obesity
19.30-Onwards Welcome mixer and dinner Fijian Villa (weather dependent)
Monday August 14th    
Session 2: Obesity Inflammation and Cancer
Session Chair: Russell Jones
    Talanoa Hall
08.30-9.00 Erwin Wagner
CNIO, Madrid, Spain
Inflammation, Metabolism and Cancer linked to AP-1
9.00-9.30 Brendan Manning
Harvard University’s T.H. Chan School of Public Health, Boston, USA
The mTOR Network and Control of Anabolic Metabolism
9.30-10.00 Christian Metallo
University of California, San Diego, USA
Tracing Links between Amino Acid and Lipid Metabolism in Cancer and Metabolic Syndrome
10.00-10.15 Short talk
Kyle Hoehn
University of NSW, Australia
Lipogenesis is Dispensable for Liver Tumourigenesis in Mice Treated with Diethylnitrosamine
Short talk
Marit Hjorth
Garvan Institute of Medical Research, Sydney, Australia
Skeletal Muscle Secretory Proteins: a Link between Regular Physical Activity and Reduced Breast Cancer Risk
Poster session and Refreshments Koral Coast Conference Centre (KCCC)
Session 3: Adipose Tissue Inflammation and Metabolic Disease
Session Chair: Andrea Hevener
    Talanoa Hall
11.00-11.30 Steve Shoelson
Harvard Medical School, Boston, USA
Molecular Mechanisms for the Anti-Inflammatory Actions of AMPK Activation Reveal Convergent Paths for Physiological Suppression of NF-kB
11.30-12.00 Alyssa Hasty
School of Medicine, Vanderbilt University, Nashville, USA
High CD8 T cell receptor clonality and altered CDR3 properties in adipose tissue of obese mice
12.00-12.30 Philipp Scherer
Touchstone Diabetes Center, University of Texas Southwestern Medical Center, Dallas, USA
The Ominous Triad of Adipose Tissue Dysfunction: Inflammation, Fibrosis and Impaired Angiogenesis
12.30-13.00 Diane Mathis
Harvard Medical School, Boston, USA
T Cell Control of Organismal Metabolism
Short talk
Kate Quinlan
University of New South Wales, Sydney, Australia
Understanding the role of Eosinophils in Adipose Tissue Energy Expenditure
13.15-14.15 Group lunch KCCC
14.15-18.00 Free time  
Session 4: Innate Immunity and Inflammasomes
Session Chair: Vishwa Deep Dixit
    Talanoa Hall
18.00-18.30 Eicke Latz
Institute of Innate Immunity, University of Bonn, Germany
Western Diet Triggers NLRP3-dependant Persistent Funtional Reprograming of Myeloid Cells
18.30-19.00 Kate Schroder
Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia
Myeloid Cell Identity Shapes Inflammasome Signalling and Cell Death Decisions
19.00-19.30 Seth Masters
Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
NLRP1 Exacerbates Inflammatory Bowel Disease Trough IL-18, Restricting Butyrate Producing Clostridiales
19.30-19.45 Short talk
Andrew Murphy
Baker Heart & Diabetes Institute, Melbourne, Australia
Mitochondrial Dysfunction in Human Cd16+ Monocyte derived M2 Macrophages is Linked to Foam Cell Formation
19.45-20.00 Short talk
Christina Camell
Yale School of Medicine, New Haven, USA
NLRP3 Inflammasome controls Adipose Tissue Macrophage Activation during Aging
20.00-Onwards Dinner  Bula Braserie
Tuesday August 15th    
  Group Breakfast  
Session 5: Microbiome and adaptive immunity
Session Chair: Erika Pearce
    Talanoa Hall
8.30-9.00  Dan Littman

Howard Hughes Medical Institute / Skirball Institute of Biomolecular Medicine of New York University School of Medicine, New York, USA

Microbiota Control of the Gut Immnune Homeostasis
9.00-9.30 Janelle Ayres
Salk Institute for biological studies, La Jolla, USA
Host-microbe Interactions: Leveraging Co-evolution to Treat Disease
9.30-10.00 Susan Kaech
Yale University, New York, USA
Anti-tumor T Cells - You Are What You Eat
10.00-10.15 Short talk
David Schneider
Department of Microbiology & Immunology, Stanford University, CA, USA
Measuring the Contribution of Host Metabolism on Tolerance and Resilience to Infections
10.15-10.30 Short talk
You-Me Kim
Pohang University of Science & Technology, Pohang, South Korea
Intestinal Th17 Cells Play a Critical Role in the Maintenance of Metabolic Homeostasis
10.30-11.00 Poster session and Refreshments   KCCC
Session 6: Cancer, Obesity & Metabolism
Session Chair:  Brendan Manning
Russell Jones
Goodman Cancer Research Centre at McGill University, Montreal, Canada
Novel Mechanisms of LKB1-mediated Tumor Suppression
Ralph DeBerardinis
The Children’s Medical Center Research Institute (CRI), University of Texas Southwestern Medical Center, Dallas, USA
Understanding Metabolic Phenotypes in Cancer Cells and Tumors
Short talk
Andre Marette
Quebec Heart & Lung Institute, Laval University, Qebec, Canada
Omega-3 PUFAs Alleviate Insulin Resistance and Hepatic Steatosis in Obese Mice through Distinct but Overlapping Mechanisms involving Activation of a Myokine-liver Signal
12.15-12.30 Short talk
John-Olov Jansson
Institute of Neuroscience & Physiology, University of Gothenburg, Sweden
Functional Interleukin-6 Receptor alpha is Localized on Tanycytes at the Base of the Third Ventricle
 12.30-1245  Short talk
Samuel Breit
St Vincent's Hospital, UNSW, Sydney, Australia
 The Tgfb Cytokine Mic-1/Gdf15 Induces Weight Loss and Corrects the Metabolic and Pro-inflammatory Phenotype of Obesity
12.45-13.00 Short Talk
Maria Sibilia
Medical University of Vienna, Austria
EGFR Expression in tumor-associated myeloid cells promotes colorectal cancer in mice and correlates with worse prognosis in CRC patients
13.00-14.00 Group lunch KCCC
14.15-18.00 Free time  
Session 7: Immune Cell Signalling, Cytokines and Metabolic Reprogramming
Session Chair: Eicke Latz
    Talanoa Hall
18.00-18.30 Vishva Dixit

Genentech, Inc., San Francisco, USA

Interplay between Regulators of Apoptosis and Necroptosis
18.30-19.00 Mark Febbraio

Garvan Institute of Medical Research, Sydney, Australia

The Engineered Cytokine IC7: a Novel Therapy for the Treatment of Metabolic Disease
19.00-19.30 Edward Pearce

Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany

Modulation of Mitochondrial Function by PGE2
19.30-20.00 Marc Donath

University of Basel, Switzerland

Islet Inflammation in Type 2 Diabetes: from Physiology to Therapy
Short talk
Ueli Nachbur
The Walter & Eliza Hall Institute, Parkville, Australia
Dissecting Nod Signalling at the Endogenous Level
20.15-Onwards Dinner  Bula Braserie
Wednesday August 16th    
  Group Breakfast  
Session 8: ImmunoMetabolism II
Session Chair:  Lydia Lynch
    Talanoa Hall
Luke O’Neill

Trinity Biomedical Sciences Institute: Trinity College, Dublin, Ireland

Krebs Cycle repurposed for Cytokines
8.30-9.00 Heather Christofk

David Geffen School of Medicine,  UCLA, Los Angeles, USA

Metabolic Transition in Cancer: Lessons from Viral Infection
9.00-9.30 Vishwa Deep Dixit

School of Medicine, Yale University, New York, USA

Immunometabolic Regulation of Aging
9.30-10.00 Maxim Artyomov

Washington University, St.Louis, USA

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
10.00-10.15 Short talk
Samuel Weinberg
Northwestern University, Chicago, IL, USA
Mitochondria Complex III is Essential to Maintain Regulatory T cell function
Short talk
David O'Sullivan
Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany
T Cell Metabolism is Altered by Febrile Range Temperature
10.30-11.00 Poster session and Refreshments
Session 9: Obesity, Inflammation and Metabolism
Session Chair : Randy Levinson
11.00-11.30 Andrew Pospisilik

Max Plank Institute of Immunobiology and Epigenetics, Freiburg, Germany

Modelling (epi)genetic Roots of Metabolic Disease
11.30-12.00 Andrea Hevener

David Geffen School of Medicine, UCLA, Los Angeles, USA

The Impact of Mitochondrial Dynamics on Macrophage Function
12.00-12.30 Carolin Daniel

Helmholtz Diabetes Center, Helmholtz Zentrum, Munich, Germany

Regulatory T cells Link Environmental Influences with Adipose Tissue Function
12.30-13.00 Takashi Kadowaki

School of Medicine, University of Tokyo, Japan

New Insight into Structure and Function of AdipoR - A central Target for Obesity-linked Disease
Short talk
Katrin Fischer
Helmholtz Diabetes Center, Helmholtz Zentrum, Munich, Germany
 Alternatively Activated Macrophages are Not Implicated in Control of Nonshivering Thermogenesis
13.15-14.15 Group lunch KCCC
14.15-18.00 Free time  
Closing Address:
Chair: Janelle Ayres

  Talanoa Hall
18-00-19.00  Douglas Green
St. Jude Children's Research Hospital, Memphis, USA
Non-canonical Autophagy and Phagocytosis:  Two Ancient Pathways Converge on Inflammation, innate immunity and aging
19.00-Onwards Farewell Drinks and Dinner  Pool Deck (weather dependent)
  Thursday August 17th  
8.30-10.30 Breakfast / Checkout (11am)








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