Program

*Program content may be subject to change.

Sunday August 13th     
14.00-17.00 Registration  Talanoa Hall
   
 
Welcome & Opening Address    Talanoa Hall

16.45-17.00
Mark Febbraio
Garvan Institute of Medical Research, Sydney, Australia
Welcome
 17.00-18.00
Erika Pearce
Max Planck Institute for Immunobiology and Epigenetics, Freiburg, Germany
Mitochondrial Shape Shifting in the T Cell Response
Session 1: Immuno-Metabolism I
Session Chair: Luke O'Neill
    Talanoa Hall
18.00-18.30 Michael Karin
University of California, San Diego, USA

18.30-19.00 Steve Bensinger
David Geffen School of Medicine, UCLA, Los Angeles, USA
Towards Understanding the Impact of Lipid Metabolic Programming in Inflammatory and Immune Responses
19.00-19.30 Navdeep Chandel
Feinberg School of Medicine, Northwestern University, Chicago, USA
Mitochondria as Signaling Organelles
19.30-19.45 Short talk
Ana Domingos
Gulbenkian Science Institute, Oeiras, Portugal
Sympathetic Obesity
19.30-Onwards Welcome mixer and dinner Fijian Villa (weather dependent)
Monday August 14th    
 
 
Session 2: Obesity Inflammation and Cancer
Session Chair: Russell Jones
    Talanoa Hall
08.30-9.00 Erwin Wagner
CNIO, Madrid, Spain
Inflammation, Metabolism and Cancer linked to AP-1
9.00-9.30 Brendan Manning
Harvard University’s T.H. Chan School of Public Health, Boston, USA
The mTOR Network and Control of Anabolic Metabolism
9.30-10.00 Christian Metallo
University of California, San Diego, USA
Tracing Links between Amino Acid and Lipid Metabolism in Cancer and Metabolic Syndrome
10.00-10.15 Short talk
Kyle Hoehn
University of NSW, Australia
Lipogenesis is Dispensable for Liver Tumourigenesis in Mice Treated with Diethylnitrosamine
10.15-10.30
Short talk
Marit Hjorth
Garvan Institute of Medical Research, Sydney, Australia
Skeletal Muscle Secretory Proteins: a Link between Regular Physical Activity and Reduced Breast Cancer Risk
10.30-11.00
Poster session and Refreshments Koral Coast Conference Centre (KCCC)
Session 3: Adipose Tissue Inflammation and Metabolic Disease
Session Chair: Andrea Hevener
    Talanoa Hall
11.00-11.30 Steve Shoelson
Harvard Medical School, Boston, USA
Molecular Mechanisms for the Anti-Inflammatory Actions of AMPK Activation Reveal Convergent Paths for Physiological Suppression of NF-kB
11.30-12.00 Alyssa Hasty
School of Medicine, Vanderbilt University, Nashville, USA
High CD8 T cell receptor clonality and altered CDR3 properties in adipose tissue of obese mice
12.00-12.30 Philipp Scherer
Touchstone Diabetes Center, University of Texas Southwestern Medical Center, Dallas, USA
The Ominous Triad of Adipose Tissue Dysfunction: Inflammation, Fibrosis and Impaired Angiogenesis
12.30-13.00 Diane Mathis
Harvard Medical School, Boston, USA
T Cell Control of Organismal Metabolism
13.00-13.15
Short talk
Kate Quinlan
University of New South Wales, Sydney, Australia
Understanding the role of Eosinophils in Adipose Tissue Energy Expenditure
13.15-14.15 Group lunch KCCC
14.15-18.00 Free time  
Session 4: Innate Immunity and Inflammasomes
Session Chair: Vishwa Deep Dixit
    Talanoa Hall
18.00-18.30 Eicke Latz
Institute of Innate Immunity, University of Bonn, Germany
Western Diet Triggers NLRP3-dependant Persistent Funtional Reprograming of Myeloid Cells
18.30-19.00 Kate Schroder
Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia
Myeloid Cell Identity Shapes Inflammasome Signalling and Cell Death Decisions
19.00-19.30 Seth Masters
Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
NLRP1 Exacerbates Inflammatory Bowel Disease Trough IL-18, Restricting Butyrate Producing Clostridiales
19.30-19.45 Short talk
Andrew Murphy
Baker Heart & Diabetes Institute, Melbourne, Australia
Mitochondrial Dysfunction in Human Cd16+ Monocyte derived M2 Macrophages is Linked to Foam Cell Formation
19.45-20.00 Short talk
Christina Camell
Yale School of Medicine, New Haven, USA
NLRP3 Inflammasome controls Adipose Tissue Macrophage Activation during Aging
20.00-Onwards Dinner  Bula Braserie
Tuesday August 15th    
  Group Breakfast  
Session 5: Microbiome and adaptive immunity
Session Chair: Erika Pearce
    Talanoa Hall
8.30-9.00  Dan Littman

Howard Hughes Medical Institute / Skirball Institute of Biomolecular Medicine of New York University School of Medicine, New York, USA

Microbiota Control of the Gut Immnune Homeostasis
9.00-9.30 Janelle Ayres
Salk Institute for biological studies, La Jolla, USA
Host-microbe Interactions: Leveraging Co-evolution to Treat Disease
9.30-10.00 Susan Kaech
Yale University, New York, USA
Anti-tumor T Cells - You Are What You Eat
10.00-10.15 Short talk
David Schneider
Department of Microbiology & Immunology, Stanford University, CA, USA
Measuring the Contribution of Host Metabolism on Tolerance and Resilience to Infections
10.15-10.30 Short talk
You-Me Kim
Pohang University of Science & Technology, Pohang, South Korea
Intestinal Th17 Cells Play a Critical Role in the Maintenance of Metabolic Homeostasis
10.30-11.00 Poster session and Refreshments   KCCC
Session 6: Cancer, Obesity & Metabolism
Session Chair:  Brendan Manning
   
11.00-11.30
Russell Jones
Goodman Cancer Research Centre at McGill University, Montreal, Canada
Novel Mechanisms of LKB1-mediated Tumor Suppression
11.30-12.00
Ralph DeBerardinis
The Children’s Medical Center Research Institute (CRI), University of Texas Southwestern Medical Center, Dallas, USA
Understanding Metabolic Phenotypes in Cancer Cells and Tumors
12.00-12.15
Short talk
Andre Marette
Quebec Heart & Lung Institute, Laval University, Qebec, Canada
Omega-3 PUFAs Alleviate Insulin Resistance and Hepatic Steatosis in Obese Mice through Distinct but Overlapping Mechanisms involving Activation of a Myokine-liver Signal
12.15-12.30 Short talk
John-Olov Jansson
Institute of Neuroscience & Physiology, University of Gothenburg, Sweden
Functional Interleukin-6 Receptor alpha is Localized on Tanycytes at the Base of the Third Ventricle
 12.30-1245  Short talk
Samuel Breit
St Vincent's Hospital, UNSW, Sydney, Australia
 The Tgfb Cytokine Mic-1/Gdf15 Induces Weight Loss and Corrects the Metabolic and Pro-inflammatory Phenotype of Obesity
12.45-13.00 Short Talk
Maria Sibilia
Medical University of Vienna, Austria
EGFR Expression in tumor-associated myeloid cells promotes colorectal cancer in mice and correlates with worse prognosis in CRC patients
13.00-14.00 Group lunch KCCC
14.15-18.00 Free time  
Session 7: Immune Cell Signalling, Cytokines and Metabolic Reprogramming
Session Chair: Eicke Latz
    Talanoa Hall
18.00-18.30 Vishva Dixit

Genentech, Inc., San Francisco, USA

Interplay between Regulators of Apoptosis and Necroptosis
18.30-19.00 Mark Febbraio

Garvan Institute of Medical Research, Sydney, Australia

The Engineered Cytokine IC7: a Novel Therapy for the Treatment of Metabolic Disease
19.00-19.30 Edward Pearce

Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany

Modulation of Mitochondrial Function by PGE2
19.30-20.00 Marc Donath

University of Basel, Switzerland

Islet Inflammation in Type 2 Diabetes: from Physiology to Therapy
20.00-20.15
Short talk
Ueli Nachbur
The Walter & Eliza Hall Institute, Parkville, Australia
Dissecting Nod Signalling at the Endogenous Level
20.15-Onwards Dinner  Bula Braserie
Wednesday August 16th    
  Group Breakfast  
Session 8: ImmunoMetabolism II
Session Chair:  Lydia Lynch
    Talanoa Hall
8.00-8.30
Luke O’Neill

Trinity Biomedical Sciences Institute: Trinity College, Dublin, Ireland

Krebs Cycle repurposed for Cytokines
8.30-9.00 Heather Christofk

David Geffen School of Medicine,  UCLA, Los Angeles, USA

Metabolic Transition in Cancer: Lessons from Viral Infection
9.00-9.30 Vishwa Deep Dixit

School of Medicine, Yale University, New York, USA

Immunometabolic Regulation of Aging
9.30-10.00 Maxim Artyomov

Washington University, St.Louis, USA

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
10.00-10.15 Short talk
Samuel Weinberg
Northwestern University, Chicago, IL, USA
Mitochondria Complex III is Essential to Maintain Regulatory T cell function
10.15-10.30
Short talk
David O'Sullivan
Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany
T Cell Metabolism is Altered by Febrile Range Temperature
10.30-11.00 Poster session and Refreshments
KCCC
Session 9: Obesity, Inflammation and Metabolism
Session Chair : Randy Levinson
   
11.00-11.30 Andrew Pospisilik

Max Plank Institute of Immunobiology and Epigenetics, Freiburg, Germany

Modelling (epi)genetic Roots of Metabolic Disease
11.30-12.00 Andrea Hevener

David Geffen School of Medicine, UCLA, Los Angeles, USA

The Impact of Mitochondrial Dynamics on Macrophage Function
12.00-12.30 Carolin Daniel

Helmholtz Diabetes Center, Helmholtz Zentrum, Munich, Germany

Regulatory T cells Link Environmental Influences with Adipose Tissue Function
12.30-13.00 Takashi Kadowaki

School of Medicine, University of Tokyo, Japan

New Insight into Structure and Function of AdipoR - A central Target for Obesity-linked Disease
13.00-13.15
Short talk
Katrin Fischer
Helmholtz Diabetes Center, Helmholtz Zentrum, Munich, Germany
 Alternatively Activated Macrophages are Not Implicated in Control of Nonshivering Thermogenesis
13.15-14.15 Group lunch KCCC
14.15-18.00 Free time  
Closing Address:
Chair: Janelle Ayres

  Talanoa Hall
18-00-19.00  Douglas Green
St. Jude Children's Research Hospital, Memphis, USA
Non-canonical Autophagy and Phagocytosis:  Two Ancient Pathways Converge on Inflammation, innate immunity and aging
19.00-Onwards Farewell Drinks and Dinner  Pool Deck (weather dependent)
  Thursday August 17th  
8.30-10.30 Breakfast / Checkout (11am)
 

 

 

 

 

 

 

 

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